Sciencewerke & HMT: Metabolomics in Infectious Disease Research
What is Metabolomics?
Metabolomics is defined as the comprehensive analysis of the types and concentrations of metabolites. When metabolism is affected by external stimuli (environmental changes such as temperature, light, drug intake, etc.) or diseases, the types, and concentrations of metabolites in the cells can also change. By analysing these metabolic changes, it is possible to search for biomarkers, and develop and test hypotheses about the organism’s metabolism.
Metabolomics Application in Infectious Disease Research
Metabolomics help to reveal specific metabolic alterations and potential biomarkers that are associated with disease severity in patients with systemic infections.
Great potential for exploring predictive and risk markers of disease development, and contributes to the treatment and prevention of infectious diseases.
HMT’s metabolome analysis employs CE-MS & LC-MS platforms. The technologies are optimized to measure metabolites related to cellular energy metabolism, e.g., amino acids, short-chain fatty acids, polyamines in most types of samples, including: