The Helios gene gun is a convenient handheld device that provides rapid and direct transfection into a range of targets in vivo. The unit uses an adjustable low-pressure helium pulse to sweep DNA-, RNA-, or biomaterial-coated gold microcarriers from the inner wall of a small plastic cartridge directly into target cells.
The Helios gene gun is a convenient handheld device that provides rapid and direct transfection into a range of targets in vivo. The unit uses an adjustable low-pressure helium pulse to sweep DNA-, RNA-, or biomaterial-coated gold microcarriers from the inner wall of a small plastic cartridge directly into target cells.
Key Features
Provides easy-to-use, rapid, versatile gene delivery independent of target cell type
Facilitates both transient and stable expression
Requires only small amounts of DNA and cells; no carrier DNA needed
Enables codelivery of more than one plasmid
Allows transfer of large DNA fragments
Targets intracellular gene delivery to many cells
Works for both in vitro and in vivo transformation
Delivers no extraneous genes or proteins