What We Do

We are a forward-thinking and innovative ‘one-stop’ solution provider of reputable life science, biomedical
and clinical equipment, reagents and consumables for the academic, institutional and private sectors.

Cellomic Solutions

Consumables and Labware

Genomic Solutions

Proteomic Solutions

Molecular Diagnostics

Pre-clinical Imaging

Highlights & Events


1st Annual Human Genomics...

Event: 1st Annual Human Genomics Symposium Date: 14th & 15th November 2019 Venue: CRC Auditorium, NUSSciencewerke participated in the 1st Annual Human Genomics Symposium, jointly hosted by National University Health System (NUHS), Genome Institute of Singapore (GIS) and NovogeneAIT Genomics Singapore. We showcased our genomics portfolio, with focus on next generation technologies for research and diagnostics, to the scientist and clinicians who are working in the fields of human genomics.


12th SALAS Annual Conference

Event: 12th SALAS Annual Conference Date: 8th & 9th November 2018 Venue: Rendevous HotelSciencewerke participated in the annual SALAS event - Advancements in laboratory animal care and management, facilitating research innovations where we showcase many of our cutting-edge technology on imaging solutions.For information on SALAS, click here


Biotech Fest @ Biopolis

  Event: Biotech fest @ Biopolis Date: 31st Oct 2018 - 1st Nov 2018 Venue: Epicentre, MatrixResearch Support Centre (RSC) held its bi-annual event, Biotech Fest @ Biopolis. Sciencewerke gave out free affogato for those who like our facebook page.  Participants played games and checked out promotions that Sciencewerke was offering. Thank you all for coming!


Seminar - How to...

High quality images of cells, which have high spatial and temporal resolution, require not only the appropriate technical equipment to create them, but also careful attention to the sample preparation. This seminar will focus on how to link optimized cell culture with cell-based assays and high-end microscopy. ibidi produces specialized chambers, with specialized geometries and high optical properties, which allow micro-scopical analysis of living or fixed cells during cultivation, treatment within the same dish or slide. In addition, ibidi provides software online that provides fully automated quantitative analysis of cell behavior. Methods such as immunofluorescence, cell migration, and chemotaxis, as well as scientific data, will be presented to give a more in depth look at ibidi’ s integrated approach to cell-based assays. In this talk, we will be focusing on how to optimize the key application and providing an all-in-one solution in:• Live Cell Imaging • Immunofluorescence • Wound Healing and Cell Migration • Chemotaxis and Angiogenesis • Cell Culture Under Flow • 3D culture of spheroids and organoids

Event details

11th Oct 2018 (Thursday) 10:00am - 11:00am NUS Confocal Microscopy Unit MD1-09-01B Presenter: Dr. Christian Leibold, Director, ibidi GmbH11th Oct 2018 (Thursday) 2:00pm - 3:00pm NUS Mechanobiology Institute T-Lab Level 5, Seminar rooms 1- 3 Presenter: Dr. Christian Leibold, Director, ibidi GmbHRefreshments will be provided for both seminars.

Please register here



SARS-CoV-2 & Flu Multiplexed Solutions

Confidently Stratify COVID-19 and Flu Patients

Whether your laboratory is utilizing multiplex or sequential molecular testing workflows, LGC SeraCare offers AccuPlex™ Quality Solutions with targets for SARS-CoV-2, influenza A/B and respiratory syncytial virus (RSV). Available as Verification Panels optimized for assay verification at installation and Reference Material Kits designed to monitor day-to-day assay performance, together these products offer an ideal solution for clinical laboratories looking for a safe and effective tool to verify and monitor molecular assay performance.

 [button link="https://www.seracare.com/SARS-CoV-2/sars-cov-2-multiplex/?utm_campaign=Coronavirus%20Launch%20March%202020&utm_medium=email&_hsmi=97830093&_hsenc=p2ANqtz--rc_dTyK6Mz1CHqFQjp5KsGJ_z4gR3oxHt6VoMjRI5fmdHv3-e_tDv5wl82nTdxTQQ33OulrWM107KSbNvWzdwtWrElA&utm_content=97830093&utm_source=hs_email" color="orange" newwindow="yes"] Learn more[/button] 

AccuPlex Quality Solutions are:

  • Non-infectious and replication deficient, enabling safe handling in contrast to viral samples
  • Fully-extractable with a real viral protein coat; superior to “naked” transcribed RNA by offering challenge to the entire molecular test procedure
  • Optimized for assay verification and day-to-day performance monitoring
  • Stable for 2 years at 2-8°C
 [button link="mailto: enquiry@sciencewerke.com" color="green" newwindow="yes"] Enquire now[/button]


Zeesan Complete COVID-19 Workflow

  Introducing Zeesan’s complete COVID-19 workflow from point of collection to extraction and detection.  Zeesan Collection kit The Saliva RNA Sample Collection Kit provides an all-in-one system for the collection, stabilization and transportation of saliva sample for RNA preservation. [button link="https://www.sciencewerke.com/all_products/saliva-sample-collection-kit/" newwindow="yes"] Find out more[/button]  Zeesan Detection kit Zeesan's Automatic and Manual Extraction Kit is intended to be used by professional users, such as technicians and physicians who are trained in molecular biological techniques. The kit provides high-quality RNA that is suitable for downstream applications, such as amplification or other enzymatic reactions.Intended Use:  1) NMPA approved in China for clinical use 2) CE marked for IVD use in Europe [button link="https://www.sciencewerke.com/all_products/virus-rna-extraction-kit/" newwindow="yes"] Find out more[/button]  Zeesan Extraction Solutions The Zeesan SLAN ® -96S real-time PCR system is intended for: 1. Clinical diagnosis in vitro; 2.General laboratory use. The Zeesan SLAN ® -96S real-time PCR system is used exclusively within a laboratory and its users should be trained in PCR technology and instrument operation and be familiar with related operations.Intended Use:   1) CFDA approved in China for clinical use 2) CE marked for IVD use in Europe [button link="https://www.sciencewerke.com/all_products/slan-96-pcr-system/" newwindow="yes"] Find out more[/button] [button link="mailto: enquiry@sciencewerke.com" type="big" color="orange" newwindow="yes"] Enquire now[/button]


Fab-TACS® Trial Kit Request

Traceless Affinity Selection
The Fab-based traceless affinity cell selection (Fab-TACS®) technology represents an affinity chromatography system for non-magnetic isolation of exosomes. It is based on Twin-Strep-tagged CD-speci c Fab fragments (Fabs), which reversibly capture and release the exosomes. The technology delivers label-free exosomes with intact biological functions in a standardized manner with highly reproducible quality. The exosomes can be isolated from different cell culture supernatants, serum and plasma.
Simple Workflow
Columns for exosomes are filled with a Strep-Tactin® coated matrix made of cell-grade agarose. Strep-tagged low affinity Fab fragments (Fab-Streps) specifically bind to the matrix. Subsequently, cell culture supernatants, serum, plasma or other preparations pass through the column. Exosomes adhere to the matrix based on the exclusive binding of the Fab-Strep to the target. Unwanted material is efficiently washed away. In a final step, the addition of biotin causes the elution of the exosomes and the Fab-Streps due to the higher affinity of biotin to Strep-Tactin®. After elution, the Fab-Streps self-dissociate from the vesicle surface. The label-free authentic exosomes are now ready for further downstream applications.In case ultra-pure exosome preparations without Biotin and Fabs are required, size exclusion chromatography or hydrostatic filtration dialysis can be performed.
High Quality Exosme Isolation

Minimal contamination by other EVs

The particle size is a critical factor in evaluating the quality of isolated exosomes. 99% of particles isolated from cell culture supernatants of mesenchymal stem cells (MSCs) fell within the range of 30 - 150 nm (A). This indicates strong exosome enrichment. In comparison, only 32% exosome-sized particles were detected after puri cation with a commercially available PEGylation kit (B), implying contamination by larger extracellular vesicles.

High content of exosome proteins

Since other same-sized non-exosome contaminants may contribute to the pool of isolated particles, the vesicles purified by our Fab- TACS® isolation technology from MSC supernatants were tested for the presence of marker proteins CD63 and Alix. Both proteins were clearly present within the purified particles (C), confirming their exosome phenotype.

Reproducible results

Depending on MSC donor, cell culture supernatant compositions may vary. Purified exosomes of three independent isolations from different MSC donors were very comparable in their size ranging from 86 nm to 90 nm average diameter. All isolations yielded around 94% of particles between 30 and 150 nm in size (D). Besides high purity, this demonstrates a high reproducibility of our Fab-TACS® exosome isolation technology.

Source-independent application

Important exosomes sources also include a variety of human bodily fluids such as blood and urine. Similar to isolations from cell culture supernatants, 96% of particles purified from human serum exhibited the typical exosome size of 30 to 150 nm (E). 

Quick and simple

Due to the surface protein specificity of the Fab-TACS® isolation technology, time-consuming centrifugation steps or extensive sample preparations are not necessary. The protocol is easy and straight-forward, permitting efficient and high quality exosome isolation also for newcomers in the field of exosome research. Additionally, the short processing time minimizes the stress of cargo contained within the exosomes.
 

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