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What We Do

We are a forward-thinking and innovative ‘one-stop’ solution provider of reputable life science, biomedical
and clinical equipment, reagents and consumables for the academic, institutional and private sectors.

Cellomic Solutions

Consumables and Labware

Genomic Solutions

Proteomic Solutions

Molecular Diagnostics

Pre-clinical Imaging

Highlights & Events

Get to the Bottom...

Get To The Bottom of Your Gut : A Multi-Omics Look Into the Stool Microbiome Date: 18 May 2022 Time: 10.30am and 1.30pm EDT (45min + Q&A)Click here to register for:

Featured SpeakerJason Byron Perez, M.Sc. Senior Product Specialist Key Learning Objectives

Understand what fecal samples consist of
Understand the challenges presented by fecal samples (degradation)
How to address these challenges
Applications with fecal samples (microbiome, virome, metabolomics, metatranscriptomics, and CRC-DNA)

About the SpeakerJason Perez has a background in veterinary and environmental microbiology, both in academia and the biotechnology industry. Jason is currently a Senior Product Specialist at Norgen Biotek Corp. with a focus on microbiome applications. His work with veterinary pathogens and complex environmental microbiomes now aid him in supporting Norgen’s customers, researchers and diagnosticians in the field and the lab.

Online Course: Cell Culture...

Want to learn everything about setting up experiments with cells under flow in 2 days?Sign up for ibidi’s online course on Cell Culture Under Flow and understand which critical factors such as shear rate, viscosity and sheer stress calculations, need to be considered to conduct your own successful flow experiments.This course is based on the biological knowledge that several adherent cell types, such as endothelial cells in a blood vessel, are exposed to shear stress in vivo. Culturing cells in vitro under perfusion simulates this mechanical stimulus and induces a more physiological behavior.We will also demonstrate helpful tips and tricks for the practical handling of ibidi Channel Slides.After the course, you will be equipped with advanced knowledge and a better understanding of the necessary tools to perform your flow experiments like an expert. No sterile working benches or cells are required to participate. Attend the course from the comfort of your office or home.ScheduleDay 1 Topics

Introduction to cell culture under flow
Physical background of liquid flow in channels
Tips and tricks for handling ibidi Channel Slides

Tips and tricks for setting up a flow experiment in the lab
Assays for special flow applications
Discussion about your own experimental aims and setups

Slots are limited! Click here to register now!

Online Course: Handling of...

Would you like to get tips and tricks on the ibidi Pump System and better understand the basic handling steps when performing an experiment with cell culture under flow?

To help you become an ibidi Pump System expert, we are pleased to invite you to our ibidi Online Course: Handling of the ibidi Pump System on 24 & 25 May 2022.

This 2.5 hour course covers all aspects of setting up the ibidi Pump System in the lab. You will learn about the different pump components and how to handle them, including both the Fluidic Unit, the Perfusion Sets, and the software for controlling the system. We will also demonstrate the stepwise process of setting up an assay with cells under flow.

After the course, you will be equipped with advanced knowledge and a better understanding of the necessary tools to perform your flow experiments using the ibidi Pump System.

No sterile working benches or cells are required to participate. Attend the course from the comfort of your office or home.

Schedule:

Introduction to cell culture under flow
ibidi Pump System overview–introduction to the individual components
Tips and tricks for setting up a flow experiment using the ibidi Pump System
Discussion about your own experimental aims and plans

Slots are limited. Click here to Register now!

Online Course: Setup and...

Would you like to get a better understanding of the basics of conducting a chemotaxis assay, as well as tips and tricks for handling the ibidi µ-Slide Chemotaxis?

To make the start of your experiments even easier, and to help you become a chemotaxis assay expert, we are pleased to invite you to our ibidi Online Course: Setup & Analysis of Chemotaxis Assays on 8 – 9 June 2022.

You will learn how to conduct a chemotaxis experiment from start to finish, including the handling of the µ-Slide Chemotaxis, 3D gel preparation, live cell imaging, single cell tracking, and data analysis. Also, characteristic parameters of directed and undirected cell migration will be evaluated.

You will also have the opportunity to interact with the ibidi experts to learn tips and tricks that can help you with your own experiments.

After the course, you will be equipped with advanced knowledge and a better understanding of the necessary tools to perform your chemotaxis experiments like an expert.

No sterile working benches or cells are required to participate. Attend the course from the comfort of your office or home.

Day 1 – Start: 4.00 pm CESTTopics

Introduction to chemotaxis and cell migration
Show and Tell: Handling of the µ-Slide Chemotaxis
Tips and Tricks: Setup of a chemotaxis experiment in 2D and 3D in the lab
Live cell imaging

End: 7.30 pm CEST (breaks included)

Day 2 – Start: 4.00 pm CESTTopics

Evaluation and analysis of chemotaxis assays
Methods of single cell tracking
Important parameters of data analysis
Sample experiments and experimental optimization

End: 7.30 pm CEST (breaks included)

Slots are limited. Click here to Register now!

1st Annual Human Genomics...

Event: 1st Annual Human Genomics Symposium Date: 14th & 15th November 2019 Venue: CRC Auditorium, NUSSciencewerke participated in the 1st Annual Human Genomics Symposium, jointly hosted by National University Health System (NUHS), Genome Institute of Singapore (GIS) and NovogeneAIT Genomics Singapore. We showcased our genomics portfolio, with focus on next generation technologies for research and diagnostics, to the scientist and clinicians who are working in the fields of human genomics.

12th SALAS Annual Conference

Event: 12th SALAS Annual Conference Date: 8th & 9th November 2018 Venue: Rendevous HotelSciencewerke participated in the annual SALAS event - Advancements in laboratory animal care and management, facilitating research innovations where we showcase many of our cutting-edge technology on imaging solutions.For information on SALAS, click here

Xenografting of Breast Cancer Cells using VitroGel System

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.In this research highlight, a joint team of researchers from Korean and Japanese cancer institutes performed a series of in vitro and in vivo experiments to investigate the expression and mode of action of the ring-finger protein RFN208. VitroGel, a xeno-free injectable hydrogel system was used for xenografting of triple-negative breast cancer cells into mice to help cell retention and test tumor growth in response to the upregulation of a ubiquitin-related ligase protein. The results show that RNF208 expression is closely associated with Vimentin-mediated aggressive cancer progression of breast cancer cells. Click here for the full research highlights. Read how VitroGel helps with this research. Do you know that xeno-free VitroGel hydrogels can be used as a Matrigel alternative for 3D cell culture research? Click here to find out more.

3 Reasons Why You Should Cultivate Endothelial Cells Under Flow

Did you know that shear stress, which is the mechanical force generated by blood flow, has a crucial impact on the biology of endothelial cells?Read ibidi’s latest blog article for the 3 good reasons why it is more physiological to cultivate cells under flow conditions.Shear Stress Influences:

Cell Signaling and Gene Expression
Cell Morphology, Cell Structure, and Organization
Cell Function and Behavior

Click here for full article.

A look at IgA responses of COVID-19 patient sera to known human autoantigens.

Studies report a link between COVID-19 disease severity and autoimmunity, with growing evidence showing development of autoantibodies as a result of long-lasting or life threatening cases of SARS-CoV-2 infection. Discover the new PEPperCHIP^® Autoimmune Human Epitope Microarray with 3,723 human B-cell epitopes associated with autoimmune diseases. The microarray enables you to:

Monitor autoantibody development in COVID-19 patient sera
Identify autoantibody responses after COVID-19 infection
Investigate autoantibody responses before and after COVID-19 vaccination
Correlate IgG or IgA autoantibodies with disease progression
Analyze autoantibody responses in animal models on the epitope level

[button link="https://www.pepperprint.com/fileadmin/user_upload/mds-new/PEPperCHIP_Autoimmune_Human_Epitope_Microarray2.pdf" color="green" newwindow="yes"] Learn more[/button]

Quantifying antibody-mediated neutralization of SARS-CoV-2 directly in serum

Quantifying antibody-mediated neutralization of SARS-CoV-2 directly in serum

New Scientific Publication

The emergence of mutant variants of SARS-CoV-2 and associated concerns about the effects of these mutations on the efficacy of vaccines and therapeutics has underscored the vital importance of understanding the antibody response to SARS-CoV-2.In our recent paper "In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum" we showcase the unique capabilities of our Fluidity One-W Serum platform and describe:

A new type of in-solution receptor-binding competition assay that quantifies the affinity, concentration, and neutralization potential of antibodies against the SARS-CoV-2 spike protein

The ability of this platform to accurately and quantitatively profile the underlying protein interactions directly in serum

If you have any questions about our technology or would like to see how the unique capabilities of the Fluidity One-W Serum can support your research, please get in touch and we will be happy to discuss your projects with you.

SARS-CoV-2 & Flu Multiplexed Solutions

Confidently Stratify COVID-19 and Flu Patients

Whether your laboratory is utilizing multiplex or sequential molecular testing workflows, LGC SeraCare offers AccuPlex™ Quality Solutions with targets for SARS-CoV-2, influenza A/B and respiratory syncytial virus (RSV). Available as Verification Panels optimized for assay verification at installation and Reference Material Kits designed to monitor day-to-day assay performance, together these products offer an ideal solution for clinical laboratories looking for a safe and effective tool to verify and monitor molecular assay performance.

[button link="https://www.seracare.com/SARS-CoV-2/sars-cov-2-multiplex/?utm_campaign=Coronavirus%20Launch%20March%202020&utm_medium=email&_hsmi=97830093&_hsenc=p2ANqtz--rc_dTyK6Mz1CHqFQjp5KsGJ_z4gR3oxHt6VoMjRI5fmdHv3-e_tDv5wl82nTdxTQQ33OulrWM107KSbNvWzdwtWrElA&utm_content=97830093&utm_source=hs_email" color="orange" newwindow="yes"] Learn more[/button]

AccuPlex Quality Solutions are:

Non-infectious and replication deficient, enabling safe handling in contrast to viral samples
Fully-extractable with a real viral protein coat; superior to “naked” transcribed RNA by offering challenge to the entire molecular test procedure
Optimized for assay verification and day-to-day performance monitoring
Stable for 2 years at 2-8°C

[button link="mailto: enquiry@sciencewerke.com" color="green" newwindow="yes"] Enquire now[/button]

Zeesan Complete COVID-19 Workflow

Introducing Zeesan’s complete COVID-19 workflow from point of collection to extraction and detection.

Zeesan Collection kit

The Saliva RNA Sample Collection Kit provides an all-in-one system for the collection, stabilization and transportation of saliva sample for RNA preservation. [button link="https://www.sciencewerke.com/all_products/saliva-sample-collection-kit/" newwindow="yes"] Find out more[/button]

Zeesan Detection kit

Zeesan's Automatic and Manual Extraction Kit is intended to be used by professional users, such as technicians and physicians who are trained in molecular biological techniques. The kit provides high-quality RNA that is suitable for downstream applications, such as amplification or other enzymatic reactions.Intended Use: 1) NMPA approved in China for clinical use 2) CE marked for IVD use in Europe [button link="https://www.sciencewerke.com/all_products/virus-rna-extraction-kit/" newwindow="yes"] Find out more[/button]

Zeesan Extraction Solutions

The Zeesan SLAN^® -96S real-time PCR system is intended for: 1. Clinical diagnosis in vitro; 2.General laboratory use. The Zeesan SLAN^® -96S real-time PCR system is used exclusively within a laboratory and its users should be trained in PCR technology and instrument operation and be familiar with related operations.Intended Use: 1) CFDA approved in China for clinical use 2) CE marked for IVD use in Europe [button link="https://www.sciencewerke.com/all_products/slan-96-pcr-system/" newwindow="yes"] Find out more[/button] [button link="mailto: enquiry@sciencewerke.com" type="big" color="orange" newwindow="yes"] Enquire now[/button]

Diagenode Summer Promotion

* Promotional prices will expire on December 31, 2021

Buy 2 get 1 free – ChIP-seq grade antibodies

Every lot is validated for specificity and sensitivity for actual ChIP

Batch-specific data available on website

100% satisfaction guarantee

DNA Methylation

Buy a RRBS kit and get a free magnetic rack 0.2ml

Choose the best solution for bisulfite conversion followed by sequencing to get DNA methylation status of your samples. Our kits contains high quality reagents to get the highest performance with an optimized user friendly protocol.

Buy Tag kit for ChIPmentation, Chipmentation or µChipmentation kit for histones 24 rxn and get one set of 24 indexes

ChIPmentation technology, based on tagmentation, enables the integration of library preparation during ChIP itself using transposase and sequencing-compatible adaptors. Unlike standard library preparation techniques that require multi-step ligation, ChIPmentation incorporates an easier and shorter protocol.

Buy a D-Plex kit and get a free magnetic rack 0.2ml

D-Plex ultrasensitive, ligation-free method utilizes the capture and amplification by tailing and switching for library preparation from ultra-low input amounts, down to 10 pg for small RNAs and 100 pg for total RNAs.

Buy a new Bioruptor and get a free Easy Shear Kit

Our Bioruptor ultrasonication system has been cited in over 4,000 publications. Excellent reproducibility from temperature control and up to 16 samples at one time. Perfect for chromatin shearing and DNA shearing and many more applications.

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Little Lunatic Trade-in Promotion 2021

TRADE-IN YOUR UV-VIS SPECTROPHOTOMETER AND UPGRADE TO LITTLE LUNATIC

Little Lunatic is there for labs that have fewer samples and lower requirements. It uses a chip-based version of the Lunatic plate to get quick concentration measurements of up to 16 samples in 5 minutes. Researchers that just need a quick check of concentration can get what they need from this little guy.

Simple Workflow

Skip the sample prep, cleaning and worrying about cross-contamination or evaporation – your samples will sit tight for up to 2 hours. Our Lunatic chips runs 16 samples in 5 minutes. Each microfluidic circuit has two fixed pathlengths built-in to cover a wide dynamic range of 0.03-275 OD. All you do is load up your samples and get kick-ass results.

Max out your biologic

Lunatic is the only system out there that can measure biologics at high-throughput and high concentration. It’s got dynamic range that covers from 0.02 mg/mL to 200 mg/mL (mAb), so run any protein without ever having to dilute again.Stop the madness of running just one protein at a time and cleaning up afterwards.

Dig up your genomic's dirt

Lunatic analysis software lets you see annoying impurities that classic A260 measurements alone mistake as your DNA or RNA. Find out exactly how much RNA, turbidity, beads and other influencers are screwing up your nucleic acid quantification.Ditch the time-sucking, dye-based prep and know right away if your samples are good to go.

Ridiculously good data

Get spot-on precision within 1% and accuracy within 2%. Using two fixed pathlengths, Lunatic gets you jaw-dropping data at both low and high protein concentrations and nails the expected concentrations every time. With the smallest sample size, the highest throughput and crazy accurate results, Lunatic is hands down the best tool out there for protein quantification.

Accuracy you can show off

Lunatic has shocking accuracy and wants to prove it. Using the Fundamentals tryptophan standards, the accuracy, precision and linearity of the instrument can be proven at any time — at the protein-relevant 280 nm wavelength and OD range of 20-225. Be confident about every sample with data that leaves no room for doubt.

Downstream ready

Smash through the USP & Ph. Eur. UV/Vis requirements for absorbance accuracy, precision, linearity, wavelength accuracy, stray light and resolution with performance verification measurements of independently certified NIST standards. Lunatic is ready when you are to get validated and make the move into QC.

Terms& Conditions

Trade-in is available to Fluorometer and UV-Vis Spectrophotometer of any brand

Trade-in Promotion is only valid from 1 May 2021 to 31 December 2021

Sciencewerke Pte Ltd reserves the right to amend, delete or add to any terms and conditions on this trade-in promotion from time to time without prior notice

Get your Chemotaxis FastTrack AI Image Analysis for FREE

Are you still manually tracking your cells? ibidi now offers a great way to save time and money!

Receive 30 free Chemotaxis FastTrack AI Image Analysis jobs when you buy a Box of µ-Slide Chemotaxis – for a limited time only*!

Order Your Box Here

The Chemotaxis FastTrack AI Image Analysis is an AI-based automated image analysis solution for single-cell tracking.

Accurate cell tracking with powerful artificial intelligence

Objective and reproducible analysis without labeling

Upload your time-lapse movies and receive analysis results within minutes without manual tracking

Not Already Familiar With Chemotaxis Assays?

Learn more through our Chemotaxis Application site and receive your free sample of the µ-Slide Chemotaxis to get started!

Request Your Free Sample Here

*This offer is valid until December 31, 2021 or while supplies last. *Register and key in voucher code found on packaging to redeem Chemotaxis FastTrack AI image Analysis jobs. *For redemption, time-lapse movies will need to be uploaded and results will be produced within minutes or hours.

AUM Biotech: FANA Oligos Promotion

Don't miss our exclusive promotions

Free Scamble Control

with every purchase of set of 4 FANA Oligos

4 FANAs per mRNA Knockdown (1 Target) at 10 nmoles

Free 1 SCR Control at 10 nmole

4 FANAs per mRNA Knockdown (1 Target) at 25 nmoles

Free 1 SCR Control at 25 nmole

4 FANAs per mRNA Knockdown (2 Target) at 10 nmoles each

Free 1 SCR Control at 25 nmole

Why use FANA Oligo For RNA Silencing

Transfection Reagents	Not Required
Specificity	FANA proprietary technology allows very high specificity for the target RNA
RISC Associated Off Targetting	None

Ease of Use in Different Model Systems

Basic Cell Line, Primary Cells & Difficult to Transfect Cells	Easy to use. No transfection reagents required. Mix FANA oligos with the cells
Fish Models	Can work in fish models (example zebrafish)
Transition from Basic Cell Lines to Primary Cells to Animal Models	Easy and convenient single step process

Toxicity	Non-toxic
Stability	Resistant to degradation by serum and cellular nucleases
Resources and Time Saving	Minimal resources needed and easy to Optimize
Cost Savings	Up to 80% more cost efficient in terms of time and money

FANA Treatment Workflow

FANA oligos uses RNase H-mediated cleavage, eliminating RISC-associated offtarget effects often observed with siRNA

FANAs directly targets RNA present within the nucleus

FANAs can be self-delivered and do not need transfection reagents or delivery agents

Ibidi: Get your sample here

3 Reasons to Use the ibidi Chambers

1.	High-resolution imaging
	The ibidi slides are ideal for a variety of microscopic techniques.
2.	Fast and simple handling
	The all-in-one chambers simplifying your protocol.
3.	Cost-effective experiments
	You only need a small number of cells and low reagent volumes.

Tailored For your Assay:

Choose From 3 Unique Solutions

Chambered Coverslips

Channel Slides

Chamber Slides, Removable

Cell culture and IF in the same well

Homogeneous cell distribution and small medium amounts

Ideal for long-term storage

Bottom	ibidi Coverslip	ibidi Coverslip	Glass slide
Microscope	Inverted	Inverted	Inverted & upright
Storage	Short-term	Short-term	Long-term

Order Your Free Sample

Fab-TACS® Trial Kit Request

Traceless Affinity Selection

The Fab-based traceless affinity cell selection (Fab-TACS®) technology represents an affinity chromatography system for non-magnetic isolation of exosomes. It is based on Twin-Strep-tagged CD-speci c Fab fragments (Fabs), which reversibly capture and release the exosomes. The technology delivers label-free exosomes with intact biological functions in a standardized manner with highly reproducible quality. The exosomes can be isolated from different cell culture supernatants, serum and plasma.

Request for Sample

Simple Workflow

Columns for exosomes are filled with a Strep-Tactin® coated matrix made of cell-grade agarose. Strep-tagged low affinity Fab fragments (Fab-Streps) specifically bind to the matrix. Subsequently, cell culture supernatants, serum, plasma or other preparations pass through the column. Exosomes adhere to the matrix based on the exclusive binding of the Fab-Strep to the target. Unwanted material is efficiently washed away. In a final step, the addition of biotin causes the elution of the exosomes and the Fab-Streps due to the higher affinity of biotin to Strep-Tactin®. After elution, the Fab-Streps self-dissociate from the vesicle surface. The label-free authentic exosomes are now ready for further downstream applications.In case ultra-pure exosome preparations without Biotin and Fabs are required, size exclusion chromatography or hydrostatic filtration dialysis can be performed.

High Quality Exosme Isolation

Minimal contamination by other EVs

The particle size is a critical factor in evaluating the quality of isolated exosomes. 99% of particles isolated from cell culture supernatants of mesenchymal stem cells (MSCs) fell within the range of 30 - 150 nm (A). This indicates strong exosome enrichment. In comparison, only 32% exosome-sized particles were detected after puri cation with a commercially available PEGylation kit (B), implying contamination by larger extracellular vesicles.

High content of exosome proteins

Since other same-sized non-exosome contaminants may contribute to the pool of isolated particles, the vesicles purified by our Fab- TACS® isolation technology from MSC supernatants were tested for the presence of marker proteins CD63 and Alix. Both proteins were clearly present within the purified particles (C), confirming their exosome phenotype.

Reproducible results

Depending on MSC donor, cell culture supernatant compositions may vary. Purified exosomes of three independent isolations from different MSC donors were very comparable in their size ranging from 86 nm to 90 nm average diameter. All isolations yielded around 94% of particles between 30 and 150 nm in size (D). Besides high purity, this demonstrates a high reproducibility of our Fab-TACS® exosome isolation technology.

Source-independent application

Important exosomes sources also include a variety of human bodily fluids such as blood and urine. Similar to isolations from cell culture supernatants, 96% of particles purified from human serum exhibited the typical exosome size of 30 to 150 nm (E).

Quick and simple

Due to the surface protein specificity of the Fab-TACS® isolation technology, time-consuming centrifugation steps or extensive sample preparations are not necessary. The protocol is easy and straight-forward, permitting efficient and high quality exosome isolation also for newcomers in the field of exosome research. Additionally, the short processing time minimizes the stress of cargo contained within the exosomes.

View Product Page

Featured Products

What's New at ibidi

Discover ibidi's latest product innovations here.

2019-nCoV (SARS-CoV-2) ELISA KITS

SignalChem’s 2019-nCoV (SARS-CoV-2) ELISA kits are important research and detection tools to study the novel SARS-CoV-2 and its molecular interactions with the host cell. Our high-quality ELISA kits can be used for the detection and quantification of SARS-CoV-2 spike protein (RBD) and human anti-SARS-CoV-2 spike protein IgG in biological and recombinant samples.

Microfiltration Products

GVS offers a comprehensive line of devices used in chemistry and biology laboratories for sample preparation. These products include: Syringe Filters, Capsule Filters, Centrifugal Filters and Bottle Top Filters as well as a complete offering of micropourous membranes, track-etched membranes and accessory devices.

Inhibitors and kinases

Adooq supplies over 6000 products with in-house validated biological and pharmacological activities, and a unique collection of over 3000 inhibitors on HDAC, PI3K, Apoptosis and more signaling pathways

LUNA-II™ Automated Cell Counter

Small yet powerful, the LUNA-II™ is cell counting convenience at its finest. Simply insert your sample and the LUNA-II™ does the rest: autofocus, adjust light, and count in just 15 seconds.

FLASHBlot transfer buffer

Ready-to-use transfer buffer. Designed for faster, more efficient protein transfer with increased sensitivity

Get In Touch
Send your request and we will get in touch with you as soon as possible.