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Bioruptor® Pico sonication device


The Diagenode Bioruptor is a state-of-the-art sonication system, cited in more than 2,000 publications. The Bioruptor can simultaneously process up to 12 samples with volume flexibility from 0.5 ml to 50 ml to accurately achieve random and unbiased shearing for different fragment ranges.

The closed tube format prevents sample cross-contamination, allowing unmatched reproducibility. Using a highly-controlled ultrasonic energy with ACT (Adaptive Cavitation Technology), a non-contact, parallel-processing and isothermal technology, the Bioruptor is ideal for chromatin shearing for chromatin immunoprecipitation (ChIP), genomic DNA shearing for next generation sequencing, RNA shearing, cell and tissue disruption, and much more.

The Bioruptor® Pico is the latest innovation in shearing and represents a new breakthrough as an all-in-one shearing system optimized for shearing micro-volumes of 5 μl to larger volumes of up to 2 ml. The built-in cooling system (Bioruptor® Cooler) ensures high precision temperature control resulting in higher quality samples.

  • All-in-one shearing solution
  • Simultaneous sonication of 6-16 samples
  • Small, light, and easy to use
  • Temperature-controlled

Ideal for

  • DNA shearing for Next-Generation-Sequencing (5 – 100 µl)
  • Chromatin shearing (10 µl – 2 ml)
  • RNA shearing
  • Protein extraction from tissues and cells
  • FFPE DNA extraction
  • Protein aggregation studies