Molecular Diagnostics

Cancer Screening

Vysis
The detection of genetic aberrations in solid tumors with DNA Fluorescence in situ Hybridization (FISH) probe technology is a powerful means to diagnose and more efficiently treat a wide range of cancers. Vysis offers a comprehensive line of direct labeled DNA probes for solid tumor assessment. Single and multi-color probe sets offer researchers and clinicians a variety of ways to identify chromosome or locus deletions, gains, or translocations that have been associated with specific types of solid tumors. These probes can be applied to a variety of sample types prepared for metaphase or interphase analysis.

FISH Probe

Vysis
Chromosome enumeration probes (CEP) are chromosome-specific FISH probes that hybridize to highly repetitive human satellite DNA sequences, usually located near centromeres. CEP signals are bright, and enable the identification and enumeration of human chromosomes in interphase and metaphase cells from fresh and archived samples. CEPs are used commonly to study polar bodies, blastomeres, prenatal samples, tumors, and hematologic malignancies.

Prenatal Screening

Vysis
Identification and characterization of chromosome anomalies in preimplantation, prenatal, and postnatal genetics is critical for predicting IVF cycle and pregnancy outcome, and future quality of life. FISH is a powerful tool for determining many types of chromosome anomalies. In addition to AneuVysion® , the only FDA-cleared product for rapid detection of aneusomy in amniotic fluid samples,Vysis offers an expansive line of DNA FISH probes for preimplantation, prenatal, and postnatal genetic testing and research

Pathogen Identification

PLEX-ID
PLEX-ID is a high-throughput bioidentification system based on combining molecular technologies, including polymerase chain reaction (PCR) and mass spectrometry analysis. It enables broad identification, detailed genotyping and characterization, and recognition of known and emerging organisms in hours, hence providing fast, actionable information for public health surveillance and preparation, biological research, biopharmaceutical development, forensics, and healthcare providers. PLEX-ID was awarded the 2009 Wall Street Journal Technology Innovation Awards.