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Bioruptor® Plus sonication device


The Bioruptor® uses a unique system to uniformly process multiple samples in sealed tubes of 0.5 ml to 50 ml capacity. The built-in cooling system (water cooler and Single Cycle Valve) ensures high precision temperature control resulting in higher quality samples. An excellent device for shearing chromatin, cell and tissue disruption and many other applications


Diagenode’s Bioruptor® Plus uses a gentle method of sonication to retain the integrity of DNA and/or biological complexes, including chromatin, protein-protein binding, protein-DNA complexes and other biochemical and biological assay systems.

The Bioruptor® Sonication System uses a sonication bath to generate indirect sonication waves, which emanate from an ultrasound element below the water tank. Because the system is gentler than other sonicators, the Bioruptor® produces better and more consistent results than with harsher sonication methods. Up to 12 closed tubes can be sonicated in parallel and the continuous rotation of tubes allows even distribution of the energy for efficient sonication. The Bioruptor® enables automation of sonication, guaranteeing higher reproducibility of results

Power Supply100 – 240 Vac
Control unit dimensions350(W) x 260(D) x 165(H) mm
Sonication unit dimensions (sonication bath)175(W) x 160(D) x 265(H) mm
Soundproof box dimensions350(W) x 350(D) x 500(H) mm
Sonication bath volume750 ml
Possibility to control water flow via connector kit for water coolerYes
Interval Timer0-60 sec. or min. (on/off cycles)
Total Weight30 Kg
Tube holderAvailable for 0.5 – 1.5 – 10 – 15 & 50 ml tubes
Number of samples to be processed simultaneously0.5 ml tubes – 12
1.5 ml tubes – 6
10 ml tubes – 6
15 ml tubes – 6
50 ml tubes – 3